Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332260 | 0.91 | POLB (0.44) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5333420 | 0.88 | MPO (0.47) | POLBALDH1A1KDM4EPPARGNR2E3 | |
| SCHEMBL5333912 | 0.86 | KDM4E (0.48) | HSD17B10POLBALDH1A1KDM4EPPARG | |
| SCHEMBL5373851 | 0.85 | HSD17B10 (0.46) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5360266 | 0.84 | HSD17B10 (0.46) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5371789 | 0.84 | HSD17B10 (0.46) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5336272 | 0.80 | HSD17B10 (0.45) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5331577 | 0.78 | MPO (0.48) | POLBALDH1A1KDM4ECCR3GAA | |
| SCHEMBL5334148 | 0.78 | POLB (0.44) | KMT2AHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL5329097 | 0.77 | DRD2 (0.52) | KMT2APOLBALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |