Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 3/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492321 | 0.88 | TSHR (0.68) | DHODHTSHRSLC7A11METAP2SLC40A1 | |
| Hydrochloric Acid SCHEMBL491745 | 0.87 | TSHR (0.67) | DHODHTSHRSLC7A11METAP2SLC40A1 | |
| SCHEMBL12032336 | 0.87 | DHODH (0.50) | DHODHTSHRMETAP2SLC40A1TDP1 | |
| SCHEMBL4786597 | 0.85 | MEN1 (0.57) | DHODHTSHRSLC7A11MCL1TDP1 | |
| SCHEMBL6012690 | 0.81 | DHODH (0.57) | DHODHTSHRTDP1MEN1RAB9A | |
| SCHEMBL17472746 | 0.78 | CTNNB1 (0.50) | TSHRSLC7A11MCL1METAP2MEN1 | |
| SCHEMBL491744 | 0.77 | TSHR (0.68) | DHODHTSHRSLC40A1MEN1RAB9A | |
| SCHEMBL1466906 | 0.75 | ALDH1A1 (0.72) | TSHRMCL1METAP2MEN1KMT2A | |
| SCHEMBL28930113 | 0.75 | METAP2 (0.62) | TSHRMCL1METAP2MEN1KMT2A | |
| SCHEMBL20598033 | 0.75 | FFAR4 (0.61) | TSHRSLC40A1TDP1AGTR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |