Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | METAP2 | P50579 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ACLY | P53396 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127963 | 0.90 | ALDH1A1 (0.69) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL13146414 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL15822907 | 0.89 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL27770303 | 0.89 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL1688339 | 0.89 | METAP2 (0.71) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL23879580 | 0.89 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL3279765 | 0.89 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL12200779 | 0.89 | CCR2 (0.73) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL9420971 | 0.86 | METAP2 (0.60) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL28637555 | 0.86 | KMT2A (0.58) | ALDH1A1KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670380-B1 | Cleaning agent, process for preparing same, and use thereof | BASF COATINGS AG (DE) | 1999-05-06 | — | — | EP | claimed |
| EP-0670380-A1 | Cleaning agent, process for preparing same, use thereof | BASF Lacke + Farben AG (DE) | 1995-09-06 | — | — | EP | claimed |
| EP-3285583-B1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3285583-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | The Regents of The University of Michigan (US) | 2018-02-28 | — | — | EP | disclosed |
| US-9884841-B2 | Small molecule inhibitors of Mcl-1 and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884841-B2 | Small molecule inhibitors of Mcl-1 and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-06 | — | — | US | disclosed |
| WO-2016172218-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016172218-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160304485-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-10-20 | — | — | US | disclosed |
| US-20160304485-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-10-20 | — | — | US | disclosed |
| CN-102395270-B | Novel compounds, pharmaceutical compositions containing same, methods of use for same, and methods for preparing same | FASGEN INC | 2014-11-12 | — | — | CN | disclosed |
| EP-0471894-A1 | Particulate toner material | AGFA-GEVAERT N.V. (BE) | 1992-02-26 | — | — | EP | disclosed |
| EP-0341536-A1 | Mixtures of alkenylsuccinic acids, arylsulfonylanthranilic acids and alkanol amines and their use as corrosion inhibitors in aqueous systems | BASF Aktiengesellschaft (DE) | 1989-11-15 | — | — | EP | disclosed |
| EP-0246570-B1 | ZINC AND/OR LEAD SALTS OF CARBOXYLIC ACIDS AND THEIR USE AS ANTICORROSIVES | BASF Lacke + Farben AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4830775-A | FOR AQUEOUS COATING SYSTEMS | BASF Lacke ± Farben Aktiengesellschaft (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0246570-A1 | Zinc and/or lead salts of carboxylic acids and their use as anticorrosives | BASF Lacke + Farben AG (DE) | 1987-11-25 | — | — | EP | disclosed |
| EP-0159291-A1 | Ink composition for the ink-jet printing process | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0103503-A2 | N-substituted amides, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-03-21 | — | — | EP | disclosed |
| EP-0094303-A1 | Amides, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1983-11-16 | — | — | EP | disclosed |
| US-4344862-A | Reaction products of sulfonamido-carboxylic acids or carboxamido-carboxylic acids with alkanolamines, and their use as low-foaming corrosion inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304485-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | MCL1, BCL2L1, BCL2L11 | ALDH1A1 611/4885KDM4E 1423/4885KMT2A 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.