Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333454 | 1.00 | KMT2A (0.47) | KMT2APOLBKDM4ENR4A2PLA2G4B | |
| SCHEMBL5329278 | 0.91 | KMT2A (0.47) | KMT2AKDM4ENR4A2PLA2G4BALDH1A1 | |
| SCHEMBL5329282 | 0.91 | KMT2A (0.47) | KMT2AKDM4ENR4A2PLA2G4BALDH1A1 | |
| SCHEMBL5814061 | 0.84 | PPARG (0.46) | POLBKDM4EPPARGPPARA | |
| SCHEMBL5814066 | 0.84 | PPARG (0.46) | POLBKDM4EPPARGPPARA | |
| SCHEMBL5815262 | 0.82 | POLB (0.41) | POLBKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL5815263 | 0.82 | POLB (0.41) | POLBKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL5314642 | 0.81 | RAB9A (0.49) | KMT2APOLBNR4A2PLA2G4BMEN1 | |
| SCHEMBL5314639 | 0.81 | RAB9A (0.49) | KMT2APOLBNR4A2PLA2G4BMEN1 | |
| SCHEMBL5815275 | 0.78 | PPARG (0.48) | POLBKDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |