Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | AKT2 | P31751 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337926 | 0.92 | CNR1 (0.58) | CNR1HPGDGABRA2GABRB2KCNK3 | |
| SCHEMBL5322233 | 0.92 | CNR1 (0.58) | CNR1HPGDGABRA2GABRB2KCNK3 | |
| SCHEMBL5339197 | 0.85 | CASP1 (0.49) | CNR1HPGDGABRA2GABRB2KCNK3 | |
| SCHEMBL15071133 | 0.85 | F2RL1 (0.60) | HPGDPTGS2MAPTALDH1A1KDM4E | |
| SCHEMBL5347759 | 0.84 | AKT1 (0.52) | HPGDAKT1AKT2SLC2A1MAPT | |
| SCHEMBL5341500 | 0.84 | KMT2A (0.60) | CNR1HPGDGABRA2GABRB2KCNK3 | |
| SCHEMBL5390922 | 0.84 | GABRA2 (0.57) | CNR1GABRA2GABRB2SLC2A1PTGS2 | |
| SCHEMBL5341068 | 0.83 | SLC2A2 (0.52) | CNR1SLC2A1 | |
| SCHEMBL5318714 | 0.83 | POLB (0.56) | CNR1HPGDGABRA2GABRB2KCNK3 | |
| SCHEMBL15071127 | 0.82 | F2RL1 (0.62) | CNR1HPGDGABRA2GABRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |