Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.86 |
| ▸ | NPC1 | O15118 | 11/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.86 |
| ▸ | TP53 | P04637 | 5/20 | 0.86 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086523 | 1.00 | RAB9A (0.86) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.93 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4106651 | 0.88 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.88 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6361263 | 0.88 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8770881 | 0.88 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.88 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.88 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6459176 | 0.87 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL12268804 | 0.87 | NPC1 (0.81) | RAB9ANPC1SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200144-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-9200142-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-9193845-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-11-24 | — | — | US | disclosed |
| US-9120914-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-09-01 | — | — | US | disclosed |
| US-20150094406-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & COMPANY | 2015-04-02 | — | — | US | disclosed |
| US-20150087757-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & COMPANY | 2015-03-26 | — | — | US | disclosed |
| US-20150087759-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & COMPANY | 2015-03-26 | — | — | US | disclosed |
| US-20150087758-A1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & COMPANY | 2015-03-26 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7230020-B2 | 11β-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| EP-1675844-A1 | PHENYL CARBOXAMIDE AND SULFONAMIDE DERIVATIVES FOR USE AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE | Sterix Limited (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20050227987-A1 | 11beta-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2005-10-13 | — | — | US | disclosed |
| WO-2005042513-A1 | PHENYL CARBOXAMIDE AND SULFONAMIDE DERIVATIVES FOR USE AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE | STERIX LIMITED (GB) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087757-A1 | THERMOPLASTIC POLYMER COMPOSITION | PARG, PUF60, MCM7 | RAB9A 4453/4885NPC1 1837/4885SMN1; SMN2 933/4885 |
| US-20050227987-A1 | 11beta-hydroxysteroid dehydrogenase inhibitors | HSD3B1, HSD3B2, HSD17B3 | RAB9A 3856/4885NPC1 1239/4885SMN1; SMN2 4243/4885 |
| US-20150087758-A1 | THERMOPLASTIC POLYMER COMPOSITION | ERCC4, SMCHD1, XRCC5 | RAB9A 4597/4885NPC1 2858/4885SMN1; SMN2 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.