SCHEMBL5334110

SCHEMBL5334110

CN1C(C)(C)CCC(=O)C1(C)C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108784 0.76
SCHEMBL15071282 0.75 TSHR (0.39) TSHRNFKB1CYP2C19MEN1ALDH1A1
SCHEMBL8463169 0.74 ALDH1A1 (0.33) ALDH1A1MAPT
SCHEMBL22832640 0.74
SCHEMBL14104841 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15071294 0.70 TSHR (0.35) TSHRNFKB1CYP2C19
SCHEMBL16527283 0.67 OTUD7B (0.33)
SCHEMBL8947410 0.67 L3MBTL1 (0.32) ALDH1A1
SCHEMBL4329315 0.65
SCHEMBL3306349 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0060558-B1 NEW DERIVATIVES OF PIPERIDINE Montedison S.p.A. (IT) 1985-07-31 EP claimed
US-4400513-A PRODUCED BY REACTING A PIPERIDONE WITH DIMETHYL SULFONIUM METHYLIDE MONTEDISON, S.P.A. (IT) 1983-08-23 US claimed
CN-103965731-A Paint composition and method for forming multi-layer coating KANSAI PAINT CO LTD 2014-08-06 CN disclosed
CN-102575116-A Aqueous coating composition KANSAI PAINT CO LTD 2012-07-11 CN disclosed
WO-2007043603-A1 COMPOSITION FOR CONDUCTIVE MATERIALS SEIKO EPSON CORPORATION (JP) 2007-04-19 WO disclosed
EP-0334424-B1 Stabilizer compounds and processes for preparing them ENIRICERCHE SPA (IT) 1993-12-22 EP disclosed
EP-0334424-A1 Stabilizer compounds and processes for preparing them ENIRICERCHE S.p.A. (IT) 1989-09-27 EP disclosed
US-4070461-A ANTICHOLESTEROL MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-01-24 US disclosed