Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 6/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376214 | 0.92 | TP53 (0.52) | LMNATP53MAPTNPC1RAB9A | |
| SCHEMBL5303639 | 0.88 | LMNA (0.44) | LMNATP53BRD4MAPTNPC1 | |
| SCHEMBL5333352 | 0.87 | ALDH1A1 (0.48) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5338164 | 0.83 | NPC1 (0.53) | LMNATP53MAPTNPC1RAB9A | |
| SCHEMBL5363955 | 0.83 | KDM4E (0.43) | MAPTNPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL10119766 | 0.79 | MAPT (0.57) | LMNATP53MAPTNPC1RAB9A | |
| SCHEMBL5304358 | 0.78 | MAPT (0.45) | TP53MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5306328 | 0.78 | F2 (0.47) | TP53MAPTRAB9AGAAKDM4E | |
| Hydrochloric Acid SCHEMBL5306307 | 0.78 | ALDH1A1 (0.43) | LMNATP53MAPTNPC1RAB9A | |
| SCHEMBL5306913 | 0.77 | CDK2 (0.40) | MAPTNPC1RAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |