Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.46 |
| ▸ | CDK2 | P24941 | 11/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334228 | 0.87 | LMNA (0.44) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL5376214 | 0.80 | TP53 (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5363955 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4ETSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL5338164 | 0.78 | NPC1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5303639 | 0.75 | LMNA (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5310087 | 0.73 | CYP1A2 (0.44) | ALDH1A1KDM4ELMNATSHRHSD17B10 | |
| SCHEMBL5306913 | 0.72 | CDK2 (0.40) | ALDH1A1KDM4ECCNE1CDK2MAPT | |
| SCHEMBL5333351 | 0.72 | CYP17A1 (0.37) | SMN1; SMN2HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL5306307 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL10119766 | 0.70 | MAPT (0.57) | LMNASMN1; SMN2MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |