Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.97 |
| ▸ | MEN1 | O00255 | 3/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.97 |
| ▸ | GLA | P06280 | 1/20 | 0.97 |
| ▸ | HPGD | P15428 | 4/20 | 0.86 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081392 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AGLAHPGD | |
| Hydrochloric Acid SCHEMBL11797478 | 0.88 | HPGD (0.84) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5661923 | 0.87 | LMNA (0.91) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5662678 | 0.87 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL6795359 | 0.87 | ALDH1A1 (0.94) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5336810 | 0.86 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5336327 | 0.86 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5663066 | 0.86 | LMNA (1.00) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL27402246 | 0.86 | GAA (0.77) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL5661692 | 0.86 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |