Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544241 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAUSP2TSHRNPC1 | |
| SCHEMBL5331656 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAUSP2TSHRNPC1 | |
| SCHEMBL5331662 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAUSP2TSHRNPC1 | |
| SCHEMBL14544239 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAUSP2TSHRNPC1 | |
| SCHEMBL14520836 | 0.86 | SLC27A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14520837 | 0.80 | CLK1 (0.60) | SMN1; SMN2LMNAUSP2TSHRNPC1 | |
| SCHEMBL14520835 | 0.80 | ALDH1A1 (0.52) | SMN1; SMN2LMNAUSP2TSHRALDH1A1 | |
| SCHEMBL5336629 | 0.77 | CLK1 (0.67) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL14520830 | 0.77 | HDAC3 (0.54) | SMN1; SMN2LMNAUSP2TSHRALDH1A1 | |
| SCHEMBL8533002 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAUSP2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | SMN1; SMN2 3872/4885LMNA 1686/4885USP2 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.