Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22215992 | 0.83 | HSD17B10 (0.52) | ALDH1A1HSD17B10MEN1LMNACYP3A4 | |
| SCHEMBL369310 | 0.79 | UCHL1 (0.43) | ALDH1A1PPOXTSHRGSK3BCES1 | |
| SCHEMBL29414113 | 0.79 | UCHL1 (0.43) | ALDH1A1PPOXTSHRGSK3BCES1 | |
| SCHEMBL5334328 | 0.77 | CDK4 (0.44) | ALDH1A1HSD17B10MEN1MAPTHPGD | |
| SCHEMBL29202777 | 0.77 | UCHL1 (0.41) | ALDH1A1PPOXTSHRCES1DNMT1 | |
| Ethane SCHEMBL29094893 | 0.74 | UCHL1 (0.39) | ALDH1A1PPOXTSHRCES1DNMT1 | |
| Ethylene SCHEMBL16860555 | 0.74 | UCHL1 (0.39) | ALDH1A1PPOXTSHRCES1DNMT1 | |
| SCHEMBL15680364 | 0.74 | PPOX (0.42) | ALDH1A1HSD17B10MEN1LMNACYP3A4 | |
| SCHEMBL28430382 | 0.73 | GSK3B (0.36) | ALDH1A1HSD17B10HPGDGSK3BGSK3A | |
| SCHEMBL13578741 | 0.71 | PPOX (0.37) | ALDH1A1MEN1MAPTKMT2APPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412763-B1 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LTD (GB) | 1996-07-10 | — | — | EP | disclosed |
| US-5219848-A | Bactericides | ICI PHARMA (FR) | 1993-06-15 | — | — | US | disclosed |