Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997014 | 0.87 | ALDH1A1 (0.64) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL14445803 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL14879973 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL5672462 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL3198374 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL16874960 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL564467 | 0.79 | ALDH1A1 (0.64) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL17997021 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL232719 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL5334117 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064291-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | CHATTOPADHYAYA JYOTI (SE) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007064291-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | CHATTOPADHYAYA JYOTI (SE) | 2007-06-07 | — | — | WO | disclosed |