Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411609 | 0.83 | MEN1 (0.86) | MEN1KMT2ATGM2MAPTCYP3A4 | |
| SCHEMBL5330329 | 0.83 | KMT2A (0.86) | MEN1KMT2AMAPTCYP3A4CYP2D6 | |
| SCHEMBL5329760 | 0.82 | MEN1 (0.84) | MEN1KMT2AMAPTCYP3A4CYP2D6 | |
| SCHEMBL18559070 | 0.82 | KMT2A (0.81) | MEN1KMT2AMAPTGAACYP3A4 | |
| SCHEMBL5334377 | 0.82 | POLB (0.67) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL15983434 | 0.81 | ALDH1A1 (0.77) | MEN1KMT2AMAPTGAACYP3A4 | |
| SCHEMBL5330934 | 0.81 | TP53 (0.76) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL5330937 | 0.81 | TP53 (0.76) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL18559215 | 0.79 | KMT2A (0.67) | MEN1KMT2AMAPTGAACYP3A4 | |
| SCHEMBL18556583 | 0.76 | RECQL (0.62) | MEN1KMT2AMAPTGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |