Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314760 | 0.83 | MEN1 (0.57) | MAPTHPGDMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5369271 | 0.82 | MEN1 (0.56) | MAPTSMN1; SMN2HPGDMAPK1MEN1 | |
| SCHEMBL5317673 | 0.79 | TSHR (0.42) | MAPTSMN1; SMN2HPGDTSHRMAPK1 | |
| SCHEMBL5311203 | 0.75 | EGFR (0.45) | MAPTSMN1; SMN2HPGDTSHRMAPK1 | |
| SCHEMBL5334156 | 0.75 | MEN1 (0.46) | MAPTHPGDMEN1KMT2AHTT | |
| SCHEMBL5378756 | 0.75 | MEN1 (0.47) | MAPTSMN1; SMN2HPGDTSHRMAPK1 | |
| SCHEMBL11523980 | 0.70 | EPHX1 (0.54) | SMN1; SMN2HPGDTSHRMAPK1MEN1 | |
| SCHEMBL5331600 | 0.69 | EPAS1 (0.52) | MEN1KMT2ATP53EGFRNPC1 | |
| SCHEMBL3794771 | 0.69 | MEN1 (0.57) | SMN1; SMN2MAPK1MEN1KMT2AHTT | |
| SCHEMBL5335403 | 0.68 | NPC1 (0.46) | MEN1KMT2AEGFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |