Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332098 | 0.81 | MEN1 (0.49) | TSHRMAPK1TP53MAPTALDH1A1 | |
| SCHEMBL5334384 | 0.79 | MAPT (0.42) | TSHRHPGDSMN1; SMN2MAPK1TP53 | |
| SCHEMBL5337352 | 0.76 | GAA (0.43) | TSHRHPGDMAPK1TP53MAPT | |
| SCHEMBL5339343 | 0.74 | ICAM1 (0.42) | HPGDSMN1; SMN2TP53MAPTALDH1A1 | |
| SCHEMBL5333560 | 0.74 | MEN1 (0.55) | HPGDSMN1; SMN2MAPK1MAPTALDH1A1 | |
| SCHEMBL5330795 | 0.73 | IRAK4 (0.47) | TSHRHPGDMAPK1TP53MAPT | |
| SCHEMBL5311203 | 0.70 | EGFR (0.45) | TSHRHPGDSMN1; SMN2MAPK1TP53 | |
| SCHEMBL5331010 | 0.70 | CSNK2A1 (0.51) | HPGDSMN1; SMN2MAPK1MAPTALDH1A1 | |
| SCHEMBL11523980 | 0.70 | EPHX1 (0.54) | TSHRHPGDSMN1; SMN2MAPK1EPHX1 | |
| SCHEMBL20278484 | 0.70 | ICAM1 (0.45) | HPGDMAPTALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |