⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410822 | 0.76 | — | — | |
| SCHEMBL221290 | 0.71 | — | — | |
| SCHEMBL7611159 | 0.69 | — | — | |
| SCHEMBL3151769 | 0.69 | — | — | |
| SCHEMBL8735793 | 0.67 | — | — | |
| SCHEMBL7879530 | 0.67 | — | — | |
| SCHEMBL9134811 | 0.67 | — | — | |
| Water SCHEMBL29104779 | 0.67 | KEAP1 (0.30) | — | |
| SCHEMBL8000441 | 0.65 | — | — | |
| SCHEMBL4921726 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369312-A | Method of producing oxo-containing azetidinone compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-18 | — | — | US | claimed |
| EP-2780326-B1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2018-12-26 | — | — | EP | disclosed |
| US-7309718-B2 | Dibenzocycloheptene compound | UBE INDUSTRIES, LTD. (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20040180884-A1 | Dibenzocycloheptene compound | UBE INDUSTRIES, LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1408033-A1 | DIBENZOCYCLOHEPTENE COMPOUND | Ube Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |