SCHEMBL5334638

SCHEMBL5334638

Nc1ccccc1OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 5/20 0.44
INPPL1 O15357 3/20 0.41
INPP5A Q14642 3/20 0.41
INPP5B P32019 2/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 2/20 0.41
RECQL P46063 1/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 2/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
PDE3A Q14432 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GPR84 Q9NQS5 1/20 0.37
MAPT P10636 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
AKT1 P31749 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569537 0.84 INPPL1 (0.57) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL28665448 0.82 INPPL1 (0.55) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL28687913 0.82 INPPL1 (0.55) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL28678394 0.82 INPPL1 (0.55) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL31276913 0.79 GAA (0.50) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL3888613 0.79 SRC (0.43) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL11801740 0.78 SRC (0.44) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL9493718 0.78 SMN1; SMN2 (0.56) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL5334635 0.76 ALDH1A1 (0.46) SRCINPPL1INPP5AINPP5BALDH1A1
SCHEMBL28335103 0.76 ALDH1A1 (0.45) SRCINPPL1INPP5AINPP5BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070142626-A1 CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH KLUGER RONALD 2007-06-21 US claimed
WO-2007065265-A1 CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH KLUGER RONALD (CA) 2007-06-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142626-A1 CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH HBG2, HBB, HBG1 SRC 1257/4885INPPL1 802/4885INPP5A 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.