SCHEMBL7202434

SCHEMBL7202434

COC(=O)c1c(Cl)c(Cl)c(Cl)c(C(=O)OC)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
ALDH1A1 P00352 3/20 0.41
NPSR1 Q6W5P4 2/20 0.40
NR4A2 P43354 1/20 0.40
KDM4E B2RXH2 3/20 0.39
CYP3A4 P08684 3/20 0.38
ACHE P22303 1/20 0.38
TSHR P16473 5/20 0.37
HSD17B10 Q99714 3/20 0.37
HPGD P15428 3/20 0.37
GLA P06280 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339188 0.97 CA12 (0.46) CA12CA1CA2CA7CA9
Dacthal SCHEMBL8827292 0.95 CA12 (0.48) CA12CA1CA2CA7CA9
Dacthal SCHEMBL53477 0.95 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL5334826 0.92 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL11696970 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL12921185 0.85 KDM4E (0.50) CA12CA1CA2CA7CA9
Dacthal SCHEMBL8539721 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL162169 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL9827003 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL8335099 0.85 ALDH1A1 (0.43) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed