Dacthal

Dacthal

SCHEMBL53477

COC(=O)c1c(Cl)c(Cl)c(C(=O)OC)c(Cl)c1Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
ALDH1A1 P00352 2/20 0.44
NPSR1 Q6W5P4 2/20 0.43
NR4A2 P43354 1/20 0.42
KDM4E B2RXH2 3/20 0.41
CYP3A4 P08684 2/20 0.40
ACHE P22303 1/20 0.40
TSHR P16473 5/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dacthal SCHEMBL8827292 1.00 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL8339188 0.97 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL7202434 0.95 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL5334826 0.92 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL12921185 0.90 KDM4E (0.50) CA12CA1CA2CA7CA9
SCHEMBL9827003 0.90 CA12 (0.41) CA12CA1CA2CA7CA9
Dacthal SCHEMBL8539721 0.90 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL11696970 0.90 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL162169 0.90 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL8335099 0.90 ALDH1A1 (0.43) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9559 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746857-A1 PRODUCTION AND DELIVERY OF THERAPEUTIC NUCLEIC ACIDS PACKAGED IN YEAST EXTRACELLULAR VESICLES EMBEDDED IN BIOCOMPATIBLE IMPLANT MATRICES Mercury Bio, Inc. (US) 2026-05-27 EP claimed
EP-4743129-A1 BONE SUBSTITUTE MATERIAL BASED ON CALCIUM SILICATE AND CALCIUM PHOSPHATE Septodont ou Septodont SAS ou Spécialités Septodont (FR) 2026-05-20 EP claimed
CN-122062679-A Unmanned ship integrated path planning method based on space-time state search and optimization 河海大学 2026-05-19 CN claimed
US-12630677-B2 Resin suitable for three-dimensional printing JAMES R. GLIDEWELL DENTAL CERAMICS, INC. (US) 2026-05-19 US claimed
CN-113901398-B Intelligent optimization method for estimated bandwidth of ship meeting situation nuclear density 集美大学 2026-05-15 CN claimed
CN-121764176-B Ship autonomous collision avoidance decision-making method and system based on cognitive entropy near-end strategy optimization 集美大学 2026-05-12 CN claimed
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20260092926-A1 BIOLOGICAL STATUS CLASSIFICATION RANDOX LABORATORIES LTD (GB) 2026-04-02 US claimed
EP-4709434-A1 CALCIUM PHOSPHATE POWDER COMPOSITION Biomimetic Innovations Limited (IE) 2026-03-18 EP claimed
US-20260070967-A1 AFFIBODY-BASED DUAL AFFINITY FUSION PROTEINS AND USES THEREOF UNIVERSITY OF OREGON (US) 2026-03-12 US claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 EP claimed
WO-1997010714-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 WO claimed
US-5441743-A In thermoplastic or thermosetting binder BATTELLE MEMORIAL INSTITUTE (US) 1995-08-15 US claimed
EP-0643773-A1 HERBICIDE RESISTANT PLANTS ZENECA LIMITED (GB) 1995-03-22 EP claimed
WO-1993024637-A1 HERBICIDE RESISTANT PLANTS ZENECA LIMITED (GB) 1993-12-09 WO claimed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO claimed
US-4894171-A SPRAYING, SPINNING, CENTRIFUGING FERMENTA PLANT PROTECTION COMPANY (US) 1990-01-16 US claimed
US-4673465-A Separation of m-xylene from o-xylene by extractive distillation with polychloro compounds BERG LLOYD 1987-06-16 US claimed
US-4627869-A DIMETHYL 2,3,5,6-TETRACHLOROTEREPHTHALATE SDS BIOTECH CORPORATION (US) 1986-12-09 US claimed