Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243083 | 0.82 | KMT2A (0.49) | SMN1; SMN2NPC1POLBALDH1A1KMT2A | |
| SCHEMBL5240550 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2NPC1POLBALDH1A1TRPV1 | |
| SCHEMBL5280780 | 0.77 | BCHE (0.52) | ALDH1A1KMT2ATSHRMAPTLMNA | |
| SCHEMBL5241937 | 0.76 | BCHE (0.44) | SMN1; SMN2NPC1POLBALDH1A1KMT2A | |
| SCHEMBL5350976 | 0.75 | KMT2A (0.55) | ALDH1A1KMT2AHTTGAATSHR | |
| SCHEMBL1219345 | 0.72 | HTT (0.66) | SMN1; SMN2NPC1POLBALDH1A1KMT2A | |
| SCHEMBL9509837 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1POLBALDH1A1KMT2A | |
| SCHEMBL22970639 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1POLBALDH1A1KMT2A | |
| SCHEMBL5466400 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2POLBALDH1A1KMT2ATSHR | |
| SCHEMBL1219835 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833797-A1 | AZACYCLIC COMPOUNDS AS INHBITORS OF SENSORY NEURONE SPECIFIC CHANNELS (SNS) | VERNALIS (R&D) LTD (GB) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006082354-A1 | AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS ( SNS ) | VERNALIS (R & D) LIMITED (GB) | 2006-08-10 | — | — | WO | disclosed |