Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 17/20 | 0.34 |
| ▸ | SELE | P16581 | 17/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 10/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20319767 | 0.76 | ALDH1A1 (0.32) | ICAM1SELEVCAM1MEN1KMT2A | |
| SCHEMBL5333499 | 0.76 | ICAM1 (0.53) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7255085 | 0.71 | ICAM1 (0.52) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7060300 | 0.71 | ICAM1 (0.57) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL5311385 | 0.71 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1FGFR1 | |
| SCHEMBL5538163 | 0.70 | CCNC (0.33) | CCNCCDK8 | |
| SCHEMBL17866234 | 0.69 | CA2 (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27702864 | 0.67 | CSNK1D (0.47) | ICAM1SELEMEN1KMT2ACCNC | |
| SCHEMBL5332254 | 0.67 | CCNC (0.35) | MEN1KMT2ACCNCCDK8FGFR1 | |
| SCHEMBL4735353 | 0.65 | KDM4E (0.47) | ICAM1SELEVCAM1ALDH1A1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496568-A | Antiinflammatory thieno [2,3-c]pyridine derivatives | PACOR (FR) | 1985-01-29 | — | — | US | claimed |
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | disclosed |