Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311385 | 0.69 | ALDH1A1 (0.35) | FGFR1MEN1GAAKMT2APOLB | |
| SCHEMBL11011064 | 0.69 | DYRK1A (0.37) | — | |
| SCHEMBL15277884 | 0.68 | PKM (0.36) | FGFR1MEN1GAAKMT2APKM | |
| SCHEMBL5334846 | 0.67 | ICAM1 (0.34) | CCNCCDK8FGFR1MEN1KMT2A | |
| SCHEMBL825761 | 0.66 | PKM (0.37) | PKMNPSR1RXFP1 | |
| SCHEMBL19097324 | 0.64 | PKM (0.35) | PKMNPSR1RXFP1 | |
| SCHEMBL31484401 | 0.63 | SMN1; SMN2 (0.35) | MEN1GAAKMT2A | |
| SCHEMBL6628787 | 0.63 | — | — | |
| SCHEMBL1997633 | 0.63 | — | — | |
| SCHEMBL5376106 | 0.63 | ALDH1A1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | disclosed |