SCHEMBL533509

SCHEMBL533509

CCCc1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.47
NISCH Q9Y2I1 1/20 0.46
LPL P06858 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HRH3 Q9Y5N1 2/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GFER P55789 1/20 0.41
RARB P10826 5/20 0.40
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MGLL Q99685 1/20 0.38
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980959 0.87 RARB (0.55) NISCHTSHRHSD17B10HRH3CA2
SCHEMBL6754529 0.87 RARB (0.55) NISCHTSHRHSD17B10HRH3CA2
SCHEMBL27629737 0.86 LPL (0.46) NISCHLPLLIPGCA2GFER
SCHEMBL17731 0.85
SCHEMBL4802707 0.85 LPL (0.54) MCL1NISCHLPLLIPGTSHR
SCHEMBL981933 0.85 HSD17B10 (0.61) LPLLIPGTSHRHSD17B10HRH3
SCHEMBL2014107 0.85 TSHR (0.47) MCL1NISCHLPLLIPGTSHR
SCHEMBL17022435 0.84 HSD17B10 (0.64) LPLLIPGTSHRHSD17B10HRH3
SCHEMBL5542220 0.84 HSD17B10 (0.64) LPLLIPGTSHRHSD17B10HRH3
SCHEMBL983507 0.84 HSD17B10 (0.64) LPLLIPGTSHRHSD17B10HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135527-A2 BENZIMIDAZOLYL COMPOUNDS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
WO-2007135529-A2 AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
EP-3606971-B1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2022-01-12 EP disclosed
CN-109071960-B Silicon-containing heterocyclic matting agents, compounds and polymers 富士胶片和光纯药株式会社 2021-01-12 CN disclosed
US-20200181359-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2020-06-11 US disclosed
US-10597511-B2 Reactive flame retardant blends for flexible polyurethane foam ICL-IP AMERICA INC. (US) 2020-03-24 US disclosed
EP-3606971-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP America Inc. (US) 2020-02-12 EP disclosed
WO-2019060035-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2019-03-28 WO disclosed
US-20190085151-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. 2019-03-21 US disclosed
EP-2275406-B1 PROCESS FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2018-11-28 EP disclosed
EP-2778160-B1 CYCLIC AZINE COMPOUND HAVING NITROGEN-CONTAINING FUSED AROMATIC GROUP, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME AS CONSTITUENT COMPONENT TOSOH CORP (JP) 2018-01-10 EP disclosed
US-4584120-A AROMATIC ESTERS HITACHI, LTD. (JP) 1986-04-22 US disclosed
EP-0087102-B1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION Hitachi, Ltd. (JP) 1985-12-18 EP disclosed
US-4528113-A Anthraquinone dye and liquid crystal composition containing the dye MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-07-09 US disclosed
US-4507221-A Anthraquinone dye and liquid crystal composition containing the same MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-03-26 US disclosed
US-4495198-A ELIMINATION OF BETA-BLOCKING ACTIVITY PENNWALT CORPORATION (US) 1985-01-22 US disclosed
EP-0120717-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-10-03 EP disclosed
EP-0120463-A2 Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1984-10-03 EP disclosed
EP-0098736-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-01-18 EP disclosed
EP-0087102-A1 Liquid crystal compound and liquid crystal composition Hitachi, Ltd. (JP) 1983-08-31 EP disclosed