SCHEMBL533531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL533036	0.82	KMT2A (0.46)	HPGDKDM4EALDH1A1MAPTCYP2C9
	SCHEMBL533265	0.79	CA12 (0.48)	ALDH1A1MAPTCYP2C9CYP2C19NPC1
	SCHEMBL533037	0.79	CA12 (0.48)	HPGDKDM4EALDH1A1MAPTLMNA
	SCHEMBL533913	0.79	ALDH1A1 (0.39)	ABL1HPGDKDM4EALDH1A1POLB
	SCHEMBL534840	0.77	CA12 (0.46)	TSHRMAOACA2
	SCHEMBL533227	0.77	GPBAR1 (0.38)	MAPTNPC1RAB9A
	SCHEMBL533031	0.76	CYP1A2 (0.45)	HPGDKDM4EALDH1A1POLBMAPT
	SCHEMBL534319	0.76	NR5A1 (0.45)	TSHRMAOACA2
	SCHEMBL534075	0.72	KIF11 (0.35)	ABL1CYP2C9LMNANPC1RAB9A
	SCHEMBL533424	0.72	ALOX15 (0.34)	ABL1HPGDALDH1A1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.