Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342659 | 0.90 | CNR1 (0.57) | SMN1; SMN2CNR1CNR2 | |
| SCHEMBL5343151 | 0.80 | CNR1 (0.49) | CNR1CNR2SPTLC1MEN1KMT2A | |
| SCHEMBL5342869 | 0.78 | CNR1 (0.53) | CNR1 | |
| SCHEMBL5343582 | 0.78 | SPTLC1 (0.45) | CNR1CNR2SPTLC1KDM4EMAPT | |
| SCHEMBL5335422 | 0.78 | SPTLC1 (0.45) | CNR1SPTLC1 | |
| SCHEMBL5351052 | 0.78 | SPTLC1 (0.50) | SMN1; SMN2SPTLC1KDM4EMAPTALOX15 | |
| SCHEMBL5337097 | 0.74 | SPTLC1 (0.53) | SMN1; SMN2CNR1CNR2SPTLC1KDM4E | |
| SCHEMBL5351259 | 0.74 | MEN1 (0.46) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL5335668 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2CNR1CYP2D6KDM4EMEN1 | |
| SCHEMBL5338836 | 0.71 | SPTLC1 (0.49) | SMN1; SMN2CNR1CNR2SPTLC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |