Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.43 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342869 | 0.96 | CNR1 (0.53) | CNR1PDE4BHTR3ANPC1RAB9A | |
| SCHEMBL5351259 | 0.82 | MEN1 (0.46) | CNR1MAPK14MEN1KMT2ACNR2 | |
| SCHEMBL5335422 | 0.82 | SPTLC1 (0.45) | CNR1HTR3ASPTLC1 | |
| SCHEMBL5343582 | 0.82 | SPTLC1 (0.45) | CNR1TTKSPTLC1CNR2 | |
| SCHEMBL5351052 | 0.82 | SPTLC1 (0.50) | SPTLC1NPC1RAB9A | |
| SCHEMBL5342659 | 0.81 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL5337097 | 0.81 | SPTLC1 (0.53) | CNR1SPTLC1CNR2 | |
| SCHEMBL5335673 | 0.80 | SMN1; SMN2 (0.55) | CNR1SPTLC1MEN1KMT2ACNR2 | |
| SCHEMBL5337260 | 0.80 | CNR1 (0.56) | CNR1SPTLC1CNR2 | |
| SCHEMBL5343953 | 0.79 | CNR1 (0.57) | CNR1SPTLC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |