Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPTLC1 | O15269 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337260 | 0.97 | CNR1 (0.56) | SPTLC1CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL5343953 | 0.96 | CNR1 (0.57) | SPTLC1CNR1CNR2CAMK2D | |
| SCHEMBL5343582 | 0.81 | SPTLC1 (0.45) | SPTLC1CNR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5335422 | 0.81 | SPTLC1 (0.45) | SPTLC1CNR1TP53MDM2NAMPT | |
| SCHEMBL5343151 | 0.81 | CNR1 (0.49) | SPTLC1CNR1CNR2 | |
| SCHEMBL5351259 | 0.79 | MEN1 (0.46) | CNR1TSHRCNR2 | |
| SCHEMBL5342869 | 0.79 | CNR1 (0.53) | CNR1 | |
| SCHEMBL5338836 | 0.78 | SPTLC1 (0.49) | SPTLC1CNR1ALDH1A1HPGDCNR2 | |
| SCHEMBL5351052 | 0.78 | SPTLC1 (0.50) | SPTLC1KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5336574 | 0.78 | TP53 (0.48) | CNR1KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |