Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889025 | 0.75 | — | — | |
| SCHEMBL889035 | 0.75 | — | — | |
| Water SCHEMBL5369986 | 0.74 | BAZ2B (0.53) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL759817 | 0.74 | — | — | |
| SCHEMBL889052 | 0.72 | BAZ2B (0.47) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL18415312 | 0.71 | BAZ2B (0.50) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL19296762 | 0.71 | BAZ2B (0.50) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL18870833 | 0.69 | BAZ2B (0.53) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL23704476 | 0.67 | BAZ2B (0.46) | BAZ2BROCK1FDPSHRH1HRH4 | |
| SCHEMBL8653202 | 0.67 | MMP2 (0.47) | BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869016-A1 | IMIDAZOLO-5-YL-2-ANILO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006095159-A1 | (IMIDAZOLO-5-YL)-2-ANILO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2006-09-14 | — | — | WO | disclosed |