Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283705 | 0.81 | MMP2 (0.46) | MMP2MMP1MMP9MMP12KDM4E | |
| SCHEMBL21298714 | 0.81 | KDM4E (0.46) | MMP2MMP1MMP9MMP12KDM4E | |
| SCHEMBL21298710 | 0.81 | MMP2 (0.46) | MMP2MMP1MMP9MMP12KDM4E | |
| SCHEMBL4251404 | 0.79 | MMP2 (0.50) | MMP2BAZ2BKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL24284378 | 0.79 | BAZ2B (0.46) | MMP2MMP1MMP9MMP12BAZ2B | |
| SCHEMBL8818379 | 0.76 | ALDH1A1 (0.47) | BAZ2BKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19913401 | 0.76 | BAZ2B (0.50) | MMP2BAZ2BLMNATSHR | |
| SCHEMBL2897266 | 0.76 | LMNA (0.46) | MMP2MMP1MMP9MMP12KDM4E | |
| SCHEMBL889025 | 0.72 | — | — | |
| SCHEMBL889035 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |