SCHEMBL5336049

SCHEMBL5336049

Cc1c(O)cccc1OC(C)OC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.41
ATM Q13315 1/20 0.41
TP53 P04637 2/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA12 O43570 2/20 0.38
CA14 Q9ULX7 2/20 0.38
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18152142 0.79 TRPA1 (0.45) TRPA1ATMTP53MAPTALDH1A1
SCHEMBL27353008 0.79 CA1 (0.40) TRPA1ATMTP53MAPTALDH1A1
SCHEMBL5336039 0.75 TRPA1 (0.41) TRPA1ATMMAPTALDH1A1LMNA
SCHEMBL12476734 0.75 TRPA1 (0.61) TRPA1ATMTP53MAPTALDH1A1
SCHEMBL11771306 0.75 CA2 (0.52) ATMTP53MAPTALDH1A1KDM4E
SCHEMBL1397111 0.75 MEN1 (0.32) ALDH1A1KDM4ECYP3A4HSD17B10MEN1
SCHEMBL27296339 0.71 F9 (0.46) TRPA1ATMTP53MAPTALDH1A1
SCHEMBL27647162 0.70 KDM4E (0.49) MAPTALDH1A1KDM4ELMNAHPGD
SCHEMBL21288 0.70 MAPT (0.67) TRPA1ATMTP53MAPTALDH1A1
SCHEMBL8747528 0.70 CA2 (0.56) ATMTP53MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007069266-A2 A NOVEL PROCESS FOR THE SYNTHESIS OF BISODPROLOL AND ITS INTERMEDIATE UNICHEM LABORATORIES LIMITED (IN) 2007-06-21 WO disclosed