Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487004 | 0.83 | HPGD (0.56) | TRPA1TP53MAPTALDH1A1LMNA | |
| SCHEMBL516150 | 0.82 | MAPT (0.44) | TRPA1ATMMAPTALDH1A1LMNA | |
| SCHEMBL2352949 | 0.81 | CA2 (0.54) | ATMTP53MAPTALDH1A1LMNA | |
| SCHEMBL5336049 | 0.79 | TRPA1 (0.41) | TRPA1ATMTP53MAPTALDH1A1 | |
| SCHEMBL27353008 | 0.77 | CA1 (0.40) | TRPA1ATMTP53MAPTALDH1A1 | |
| SCHEMBL12476734 | 0.76 | TRPA1 (0.61) | TRPA1ATMTP53MAPTALDH1A1 | |
| SCHEMBL27296339 | 0.75 | F9 (0.46) | TRPA1ATMTP53MAPTALDH1A1 | |
| SCHEMBL2962387 | 0.75 | KMT2A (0.47) | TP53ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL11012886 | 0.75 | KMT2A (0.47) | TP53ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL27647162 | 0.74 | KDM4E (0.49) | MAPTALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9980893-B2 | Dye composition comprising a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound | L'OREAL (FR) | 2018-05-29 | — | — | US | disclosed |
| US-20160303018-A1 | DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND | L'OREAL (FR) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303018-A1 | DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND | CBR3, AOC3, NOX3 | TRPA1 574/4885ATM 4339/4885TP53 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.