SCHEMBL533622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7040682	0.86	GRM5 (0.37)	GRM5OPRM1MEN1OPRD1KMT2A
	SCHEMBL31150986	0.85	GRM5 (0.37)	GRM5OPRM1MEN1OPRD1KMT2A
	SCHEMBL534621	0.84	GSTO1 (0.34)	GSTO1F2MCL1CSNK2A2CSNK2A1
	SCHEMBL534536	0.83	NR1H2 (0.34)	GSTO1F2MCL1CSNK2A2CSNK2A1
	SCHEMBL533883	0.83	GSTO1 (0.38)	GSTO1F2MCL1
	SCHEMBL534154	0.83	CYP1A2 (0.52)	KMT2A
	SCHEMBL534122	0.80	GSTO1 (0.34)	GSTO1F2MCL1
	SCHEMBL534121	0.80	GSTO1 (0.34)	GSTO1F2MCL1
	SCHEMBL959885	0.80	GRM5 (0.38)	GRM5OPRM1MEN1OPRD1KMT2A
	SCHEMBL7500028	0.80	POLB (0.52)	MEN1KMT2AALOX15TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.