Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340346 | 0.85 | MAPT (0.43) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5268051 | 0.83 | MAPT (0.42) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5272473 | 0.78 | MAPT (0.46) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5268671 | 0.76 | KDM4E (0.52) | MAPTALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL5274523 | 0.73 | MAPT (0.42) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5266671 | 0.72 | POLB (0.41) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5570201 | 0.70 | MAPT (0.46) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5512949 | 0.70 | MAPT (0.46) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5345272 | 0.70 | MAPT (0.40) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5268590 | 0.69 | ALDH1A1 (0.55) | MAPTALDH1A1HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |