Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.40 |
| ▸ | GABRP | O00591 | 4/20 | 0.40 |
| ▸ | GABRD | O14764 | 4/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.40 |
| ▸ | GABRE | P78334 | 4/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268051 | 0.85 | MAPT (0.42) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5276098 | 0.84 | MAPT (0.44) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5274888 | 0.84 | KDM4E (0.49) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5271822 | 0.82 | MAPT (0.49) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5269996 | 0.81 | MAPT (0.40) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5340346 | 0.76 | MAPT (0.43) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5264728 | 0.76 | ALDH1A1 (0.57) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5273322 | 0.74 | GABRA1 (0.49) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5336428 | 0.70 | MAPT (0.39) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5512949 | 0.69 | MAPT (0.46) | MAPTGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |