Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299767 | 0.89 | MCL1 (0.50) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL29806171 | 0.88 | MCL1 (0.52) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL299768 | 0.88 | MCL1 (0.52) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL14930073 | 0.85 | HSD17B3 (0.63) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL7459816 | 0.84 | MCL1 (0.56) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL13901263 | 0.83 | NPC1 (0.45) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL13058664 | 0.82 | HSD17B3 (0.58) | KDM4EMEN1KMT2AMCL1AKR1B1 | |
| SCHEMBL16010022 | 0.81 | KDM4E (0.42) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL16010021 | 0.81 | MCL1 (0.42) | KDM4ELMNANPC1MEN1KMT2A | |
| SCHEMBL6403952 | 0.80 | MCL1 (0.49) | KDM4ELMNANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304168-B2 | Photo-caged fluorescent molecules | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-12-04 | — | — | US | disclosed |
| US-7304168-B2 | Photo-caged fluorescent molecules | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-12-04 | — | — | US | disclosed |
| US-20050042662-A1 | Photo-caged fluorescent molecules | BOARD OF REGENTS (US) | 2005-02-24 | — | — | US | disclosed |
| US-6472541-B2 | HALOGENATED- COUMARIN, QUINOLINE-2-ONE, XANTHENE, THIOXANTHENE, SELENOXANTHENEN, OR ANTHRACENE DERIVATIVES; IRRADIATING TO CONTROL THE RELEASE OF THE SOMPOUND SPATIALLY AND TEMPORALLY TO PROBE ITS BIOLOGICAL EFFECTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-10-29 | — | — | US | disclosed |
| EP-1151350-A4 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | UNIV CALIFORNIA (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-02-07 | — | — | US | disclosed |
| EP-1151350-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | The Regents of the University of California (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000031588-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | ERCC4, XPA, GPX4 | KDM4E 4063/4885LMNA 1274/4885NPC1 1261/4885 |
| US-20050042662-A1 | Photo-caged fluorescent molecules | GJA1, GJB2, CBX7 | KDM4E 2881/4885LMNA 431/4885NPC1 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.