Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 5/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751411 | 0.90 | GABRA2 (0.47) | GABRA2GABRB2NPSR1TARBP2ALDH1A1 | |
| SCHEMBL6532756 | 0.84 | GABRA2 (0.59) | GABRA2GABRB2NPSR1TARBP2MAPT | |
| SCHEMBL5339175 | 0.78 | TARBP2 (0.46) | GABRA2GABRB2NPSR1TARBP2ALDH1A1 | |
| SCHEMBL5339179 | 0.78 | TARBP2 (0.46) | GABRA2GABRB2NPSR1TARBP2ALDH1A1 | |
| SCHEMBL5339713 | 0.77 | CNR1 (0.50) | GABRA2GABRB2MAPTKMT2AKDM4E | |
| SCHEMBL5339786 | 0.76 | OPRL1 (0.42) | GABRA2GABRB2NPSR1TARBP2ALDH1A1 | |
| SCHEMBL5341290 | 0.76 | GABRA2 (0.46) | GABRA2GABRB2NPSR1TARBP2ALDH1A1 | |
| SCHEMBL10057707 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1CYP19A1MAPT | |
| SCHEMBL2677617 | 0.73 | NPSR1 (0.60) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6357570 | 0.72 | CNR1 (0.57) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241788-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7230024-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC (US) | 2007-06-12 | — | — | US | disclosed |
| US-7145012-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20060205948-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2006-09-14 | — | — | US | disclosed |
| US-20060205720-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2006-09-14 | — | — | US | disclosed |
| EP-1622909-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004094429-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040214855-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205720-A1 | Cannabinoid receptor ligands and uses thereof | CNR2, CNR1, GPR18 | GABRA2 32/4885GABRB2 59/4885NPSR1 15/4885 |
| US-20060205948-A1 | Cannabinoid receptor ligands and uses thereof | CNR2, CNR1, GPR18 | GABRA2 32/4885GABRB2 59/4885NPSR1 15/4885 |
| US-20040214855-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | GABRA2 34/4885GABRB2 58/4885NPSR1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.