Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 12/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751411 | 0.89 | GABRA2 (0.47) | GABRA2GABRB2MAPTGAANPSR1 | |
| SCHEMBL4503440 | 0.86 | GABRA2 (0.64) | GABRA2GABRB2MAPTGAANPSR1 | |
| SCHEMBL5336458 | 0.84 | GABRA2 (0.47) | GABRA2GABRB2MAPTNPSR1TARBP2 | |
| SCHEMBL6357570 | 0.82 | CNR1 (0.57) | MAPTCNR1CNR2KDM4E | |
| SCHEMBL5339179 | 0.77 | TARBP2 (0.46) | GABRA2GABRB2MAPTGAANPSR1 | |
| SCHEMBL5339175 | 0.77 | TARBP2 (0.46) | GABRA2GABRB2MAPTGAANPSR1 | |
| SCHEMBL4187487 | 0.77 | CNR1 (0.59) | GABRA2GABRB2MAPTCNR1CNR2 | |
| SCHEMBL5339713 | 0.75 | CNR1 (0.50) | GABRA2GABRB2MAPTCNR1CNR2 | |
| SCHEMBL5341290 | 0.74 | GABRA2 (0.46) | GABRA2GABRB2MAPTGAANPSR1 | |
| SCHEMBL4510979 | 0.74 | GABRA2 (1.00) | GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |