Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15518242 | 1.00 | CTSB (0.31) | CTSBCTSKCTSLCTSSCTSD | |
| SCHEMBL15864776 | 0.83 | SLC7A5 (0.34) | CTSD | |
| SCHEMBL21843036 | 0.80 | BACE1 (0.36) | CTSBCTSKCTSDCTSEBACE1 | |
| SCHEMBL16549357 | 0.79 | BACE1 (0.38) | CTSBCTSDCTSEBACE1 | |
| SCHEMBL16549401 | 0.79 | BACE1 (0.38) | CTSBCTSDCTSEBACE1 | |
| SCHEMBL31634286 | 0.77 | ALDH1A1 (0.41) | CTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL16549396 | 0.77 | ALDH1A1 (0.33) | CTSBCTSKCTSDCTSEBACE1 | |
| SCHEMBL31634285 | 0.76 | ALDH1A1 (0.40) | CTSDCTSEBACE1ALDH1A1 | |
| SCHEMBL27742237 | 0.76 | BACE1 (0.39) | CTSDCTSEBACE1 | |
| SCHEMBL30522092 | 0.76 | ALDH1A1 (0.35) | CTSBCTSKALDH1A1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868582-A1 | NANOPARTICULATE AND CONTROLLED RELEASE COMPOSITIONS COMPRISING CYCLOSPORINE | Elan Pharma International Limited (IE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110802-A1 | NANOPARTICULATE AND CONTROLLED RELEASE COMPOSITIONS COMPRISING CYCLOSPORINE | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2006-10-19 | — | — | WO | disclosed |