Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | CTSE | P14091 | 3/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16549357 | 0.82 | BACE1 (0.38) | FURINPCSK6CTSDBACE1CTSE | |
| SCHEMBL16549401 | 0.82 | BACE1 (0.38) | FURINPCSK6CTSDBACE1CTSE | |
| SCHEMBL30522092 | 0.79 | ALDH1A1 (0.35) | ALDH1A1CTSBCTSKCACNA1BMMP2 | |
| SCHEMBL21843036 | 0.78 | BACE1 (0.36) | ALDH1A1CTSDBACE1CTSECTSB | |
| SCHEMBL15518242 | 0.77 | CTSB (0.31) | ALDH1A1CTSDBACE1CTSECTSB | |
| SCHEMBL5336503 | 0.77 | CTSB (0.31) | ALDH1A1CTSDBACE1CTSECTSB | |
| SCHEMBL17305536 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CTSDLAP3CTSBCTSK | |
| SCHEMBL30522096 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CTSDLAP3CTSBCTSK | |
| SCHEMBL17920203 | 0.77 | MMP9 (0.43) | ALDH1A1CTSBCTSKMMP2MMP9 | |
| SCHEMBL13521930 | 0.77 | MMP9 (0.43) | ALDH1A1CTSBCTSKMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150065433-A1 | CYCLOSPORIN ANALOGS | ALLERGAN, INC. (US) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065433-A1 | CYCLOSPORIN ANALOGS | CHP1, TSLP, PPP3R1 | ALDH1A1 4113/4885FURIN 4565/4885PCSK6 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.