1-Naphthol

1-Naphthol

SCHEMBL5336584

C.CO.Oc1cccc2ccccc12

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.85
PTPN22 Q9Y2R2 1/20 0.50
IDO1 P14902 1/20 0.50
PLAU P00749 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPKAPK2 P49137 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
NQO2 P16083 1/20 0.48
HSD17B10 Q99714 3/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP2A6 P11509 2/20 0.48
APP P05067 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CASP1 P29466 1/20 0.48
SNCA P37840 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL10627914 0.97 CYP1A2 (0.90) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL9292016 0.95 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL11414667 0.95 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL3416 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL10486461 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL273260 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL29767730 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL29209223 0.90 CYP1A2 (0.85) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL8219136 0.90 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL8904232 0.90 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270916-B2 Recording medium KABUSHIKI KAISHA TOSHIBA (JP) 2007-09-18 US disclosed
US-20050026079-A1 Recording medium PARALLEL WIRELESS, INC. 2005-02-03 US disclosed