Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338892 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27241733 | 0.80 | KMT2A (0.52) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27241746 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL17971409 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27241755 | 0.78 | KDR (0.48) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL7219981 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27544440 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27241720 | 0.75 | PLA2G2A (0.58) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL27241775 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL16681058 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |