Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | AKT2 | P31751 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337506 | 0.85 | PHGDH (0.51) | SMN1; SMN2HPGDNPC1RAB9ATP53 | |
| SCHEMBL5340948 | 0.82 | EPAS1 (0.46) | SMN1; SMN2HPGDNPC1RAB9ATP53 | |
| SCHEMBL5341020 | 0.77 | AKT1 (0.50) | AKT1AKT2 | |
| SCHEMBL5351210 | 0.76 | CNR1 (0.54) | HPGDNPC1RAB9AAKT1AKT2 | |
| SCHEMBL5342230 | 0.75 | CNR1 (0.56) | HPGDNPC1RAB9AAKT1AKT2 | |
| SCHEMBL5342400 | 0.74 | AKT1 (0.50) | AKT1AKT2CYP3A4 | |
| SCHEMBL5335702 | 0.73 | POLB (0.51) | TP53ALDH1A1AKT1AKT2CYP3A4 | |
| SCHEMBL5341021 | 0.71 | AKT1 (0.49) | SMN1; SMN2NPC1RAB9ADPP4DPP8 | |
| SCHEMBL5380026 | 0.70 | GABRA2 (0.49) | TP53AKT1AKT2CYP3A4 | |
| SCHEMBL5345220 | 0.69 | KDM4E (0.59) | SMN1; SMN2HPGDNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |