Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PHGDH | O43175 | 1/20 | 0.56 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337926 | 0.89 | CNR1 (0.58) | HPGDSLC2A1CNR1KMT2A | |
| SCHEMBL5322233 | 0.89 | CNR1 (0.58) | HPGDSLC2A1CNR1KMT2A | |
| SCHEMBL5342501 | 0.87 | CCNC (0.45) | KDM4ESMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL5318714 | 0.87 | POLB (0.56) | KDM4ESMN1; SMN2ALDH1A1HPGDSLC2A1 | |
| SCHEMBL5341068 | 0.87 | SLC2A2 (0.52) | SLC2A2SLC2A1CNR1 | |
| SCHEMBL1691887 | 0.86 | SLC2A2 (0.61) | KDM4ESMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL5344690 | 0.85 | LMNA (0.54) | SMN1; SMN2ALDH1A1SLC2A1AKR1C3RAB9A | |
| SCHEMBL5339197 | 0.84 | CASP1 (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDSLC2A2 | |
| SCHEMBL5319613 | 0.83 | SLC2A1 (0.52) | KDM4ESMN1; SMN2ALDH1A1HPGDSLC2A2 | |
| SCHEMBL5341500 | 0.83 | KMT2A (0.60) | HPGDSLC2A1CNR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |