Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344142 | 0.90 | PDE4B (0.39) | TP53MDM2CNR2PDE4BPDE4D | |
| SCHEMBL5337097 | 0.78 | SPTLC1 (0.53) | TP53MDM2KDM4EALDH1A1HPGD | |
| SCHEMBL5337260 | 0.75 | CNR1 (0.56) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5343953 | 0.74 | CNR1 (0.57) | CNR2CNR1L3MBTL1 | |
| SCHEMBL5341359 | 0.67 | NPC1 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5336571 | 0.67 | CNR1 (0.46) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5344217 | 0.65 | LMNA (0.51) | TP53ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5335055 | 0.65 | NAMPT (0.46) | KDM4EALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL17460377 | 0.65 | HPGD (0.55) | ALDH1A1HPGDCNR2CNR1PDE4B | |
| SCHEMBL6359381 | 0.64 | HDAC3 (0.71) | HPGDTSHRL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |