Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | GALR3 | O60755 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357370 | 0.86 | MAPT (0.44) | MAPTGALR3THRBKMT2ANPSR1 | |
| SCHEMBL11367905 | 0.86 | MAPT (0.44) | MAPTGALR3THRBMEN1KMT2A | |
| SCHEMBL6400028 | 0.84 | PDE4B (0.48) | MAPTGALR3THRBTDP1MEN1 | |
| SCHEMBL9571268 | 0.83 | HRH3 (0.45) | MAPTGALR3THRBTDP1MEN1 | |
| SCHEMBL11366945 | 0.78 | HRH3 (0.42) | MAPTGALR3THRBMEN1KMT2A | |
| SCHEMBL6401437 | 0.78 | PDE3B (0.42) | MAPTGALR3THRBALDH1A1PDE3B | |
| SCHEMBL5184219 | 0.77 | HRH3 (0.46) | MAPTGALR3THRBCYP3A4PDE3B | |
| SCHEMBL6400233 | 0.76 | PDE4B (0.52) | TDP1TSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL10333086 | 0.75 | MAPT (0.59) | MAPTGALR3THRBTDP1MEN1 | |
| SCHEMBL14491901 | 0.75 | HRH3 (0.42) | MAPTGALR3THRBPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060605-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | FLAUMENHAFT ROBERT C | 2007-03-15 | — | — | US | disclosed |
| US-7166612-B2 | Methods for reducing platelet activation platelet aggregaton or thrombosis | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040147540-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | BETH ISRAEL DEACONESS MEDICAL CENTER | 2004-07-29 | — | — | US | disclosed |
| EP-1406621-A2 | COMPOSITIONS AND METHODS FOR INHIBITING PLATELET ACTIVATION AND THROMBOSIS | Beth Israel Deaconess Medical Center (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003001968-A2 | COMPOSITIONS AND METHODS FOR INHIBITING PLATELET ACTIVATION AND THROMBOSIS | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060605-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | PLA2G7, PLTP, PLAAT2 | MAPT 4507/4885GALR3 3340/4885THRB 3454/4885 |
| US-20040147540-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | PLA2G7, PLTP, PLAAT2 | MAPT 4507/4885GALR3 3340/4885THRB 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.