SCHEMBL5337190

SCHEMBL5337190

COC(=O)C(C#N)=Cc1ccc(C)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
KMT2A Q03164 6/20 0.54
MAPT P10636 5/20 0.54
KDM4E B2RXH2 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
MEN1 O00255 4/20 0.52
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51
EGFR P00533 1/20 0.50
ERBB2 P04626 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA2B P29275 1/20 0.50
ADORA1 P30542 1/20 0.50
USP2 O75604 1/20 0.50
RECQL P46063 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.48
MAPK1 P28482 1/20 0.48
CASP3 P42574 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14413763 1.00 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL10413551 0.93 KDM4E (0.59) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL10413552 0.93 KDM4E (0.59) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL19506137 0.87 EGFR (0.65) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL782201 0.87 ALDH1A1 (0.65) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL13376833 0.87 ALDH1A1 (0.65) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL782202 0.87 ALDH1A1 (0.65) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL21457589 0.85 KDM4E (0.57) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL21457723 0.85 ALDH1A1 (0.60) ALDH1A1KMT2AMAPTKDM4ETDP1
SCHEMBL21457720 0.85 ALDH1A1 (0.60) ALDH1A1KMT2AMAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
US-20180030161-A1 COMPOSITION KIT, LAMINATE AND METHOD FOR PRODUCING SAME, AND BANDPASS FILTER FUJIFILM CORPORATION (JP) 2018-02-01 US disclosed
US-20180030161-A1 COMPOSITION KIT, LAMINATE AND METHOD FOR PRODUCING SAME, AND BANDPASS FILTER FUJIFILM CORPORATION (JP) 2018-02-01 US disclosed
US-9782748-B2 Synthesis of polymeric ionic liquids using a photochemical polymerization process THE UNIVERSITY OF TOLEDO (US) 2017-10-10 US disclosed
EP-1631432-B1 COMPOSITIONS AND A METHOD FOR IMPROVING REHEAT RATE OF PET USING ACTIVATED CARBON EASTMAN CHEM CO (US) 2010-09-08 EP disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-7291449-B2 Silver halide photographic material and methine dye FUJIFILM CORPORATION (JP) 2007-11-06 US disclosed
WO-2007098835-A1 AMINO PYRYMIDINE DERIVATIVES MERCK PATENT GMBH (DE) 2007-09-07 WO disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-20070054224-A1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-7183044-B2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed