SCHEMBL782202

SCHEMBL782202

COC(=O)/C(C#N)=C/c1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
KDM4E B2RXH2 3/20 0.65
CYP3A4 P08684 2/20 0.65
HPGD P15428 2/20 0.65
CISD1 Q9NZ45 2/20 0.65
SLC16A3 O15427 1/20 0.65
SLC16A1 P53985 1/20 0.65
GPR35 Q9HC97 1/20 0.65
KMT2A Q03164 5/20 0.62
MEN1 O00255 4/20 0.62
EGFR P00533 1/20 0.57
CYP1A2 P05177 1/20 0.57
PKM P14618 1/20 0.57
TSHR P16473 1/20 0.57
MAPK1 P28482 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
HIF1A Q16665 1/20 0.57
HSD17B10 Q99714 1/20 0.57
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782201 1.00 ALDH1A1 (0.65) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL13376833 1.00 ALDH1A1 (0.65) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL10413551 0.93 KDM4E (0.59) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL10413552 0.93 KDM4E (0.59) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL5337190 0.87 ALDH1A1 (0.54) ALDH1A1KDM4EKMT2AMEN1EGFR
SCHEMBL19506137 0.87 EGFR (0.65) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL14413763 0.87 ALDH1A1 (0.54) ALDH1A1KDM4EKMT2AMEN1EGFR
SCHEMBL21457723 0.85 ALDH1A1 (0.60) ALDH1A1KDM4ESLC16A1KMT2AMEN1
SCHEMBL21457302 0.85 ALDH1A1 (0.53) ALDH1A1KDM4ECISD1SLC16A1KMT2A
SCHEMBL21457305 0.85 ALDH1A1 (0.53) ALDH1A1KDM4ECISD1SLC16A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070224688-A1 Peptide or protein-capturing surfaces for high throughput MALDI mass spectrometry FEUER BERNICE I 2007-09-27 US claimed
US-7160680-B2 Mutation analysis by mass spectrometry using photolytically cleavable primers BRUKER SAXONIA ANALYTIK GMBH (DE) 2007-01-09 US claimed
US-20060261267-A1 Composite MALDI matrix material and methods of using it and kits thereof in MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-11-23 US claimed
WO-2006124003-A1 COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-11-23 WO claimed
US-20040043497-A1 Peptide or protein-capturing surfaces for high throughput MALDI mass spectrometry CORNING INCORPORATED 2004-03-04 US claimed
US-20040038234-A1 Sample generation for genotyping by mass spectrometry CONSORTIUM NATIONAL DE RECHERCHE EN GENOMIQUE (FR) 2004-02-26 US claimed
EP-1297181-A2 SAMPLE GENERATION FOR GENOTYPING BY MASS SPECTROMETRY Centre National de Genotype (FR) 2003-04-02 EP claimed
US-6503710-B2 Providing an amount of DNA containing the mutation, adding primers and a set of modified non-terminating nucleotide triphosphates (NTP) and terminating nucleotide triphosphates for the method of primer extension; hybridization; decomposing BRUKER DALTONIK GMBH (DE) 2003-01-07 US claimed
US-20020187493-A1 Mutation analysis by mass spectrometry using photolytically cleavable primers BRUKER SAXONIA ANALYTIK GMBH (DE) 2002-12-12 US claimed
US-20020162622-A1 Providing an amount of DNA containing the mutation, adding primers and a set of modified non-terminating nucleotide triphosphates (NTP) and terminating nucleotide triphosphates for the method of primer extension; hybridization; decomposing BRUKER DALTONIK GMBH (DE) 2002-11-07 US claimed
EP-1234888-A2 Mutation analysis by mass spectrometry using photolytically cleavable primers BRUKER-SAXONIA ANALYTIK GMBH (DE) 2002-08-28 EP claimed
EP-1170379-A1 Sample generation for genotyping by mass spectrometry Centre National de Genotypage (FR) 2002-01-09 EP claimed
WO-2002000931-A2 SAMPLE GENERATION FOR GENOTYPING BY MASS SPECTROMETRY CENTRE NATIONAL DE GENOTYPAGE (FR) 2002-01-03 WO claimed
CN-117192671-A Polarizing plate with phase difference layer 日东电工株式会社 2023-12-08 CN disclosed
CN-117192672-A Resin film, method for producing resin film, and method for producing phase difference film 日东电工株式会社 2023-12-08 CN disclosed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
WO-1989007622-A1 CONDENSATION POLYMER CONTAINING THE RESIDUE OF AN ACYLOXYSTYRYL COMPOUND AND SHAPED ARTICLES PRODUCED THEREFROM EASTMAN KODAK COMPANY (US) 1989-08-24 WO disclosed
US-4826903-A Condensation polymer containing the residue of an acyloxystyrl compound and shaped articles produced therefrom EASTMAN KODAK COMPANY (US) 1989-05-02 US disclosed
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4075162-A BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed