Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.79 |
| ▸ | MTNR1A | P48039 | 15/20 | 0.77 |
| ▸ | NQO2 | P16083 | 5/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5339402 | 0.99 | MTNR1B (0.77) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5339396 | 0.88 | MTNR1B (0.77) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5338280 | 0.88 | MTNR1B (1.00) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5338262 | 0.87 | MTNR1A (1.00) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5342504 | 0.87 | NQO2 (1.00) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL7830521 | 0.85 | NQO2 (0.67) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5346051 | 0.84 | MTNR1A (0.74) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5343419 | 0.84 | MTNR1A (0.70) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5340186 | 0.83 | MTNR1A (0.69) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL5340422 | 0.83 | MTNR1B (0.73) | MTNR1BMTNR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123529-A1 | Substituted biphenyl compounds | LES LABORATOIRES SERVIER (FR) | 2007-05-31 | — | — | US | disclosed |
| US-7183318-B2 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2007-02-27 | — | — | US | disclosed |
| US-7161035-B2 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2007-01-09 | — | — | US | disclosed |
| US-20040014969-A1 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-01-22 | — | — | US | disclosed |
| US-20040002490-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LESIEUR DANIEL (FR) | 2004-01-01 | — | — | US | disclosed |
| US-20040002491-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LESIEUR DANIEL (FR) | 2004-01-01 | — | — | US | disclosed |
| US-6605632-B1 | Affinity for melatonin receptors | LES LABORATOIRES SERVIER (FR) | 2003-08-12 | — | — | US | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014969-A1 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | MTNR1A, MTNR1B, MC2R | MTNR1B 2/4885MTNR1A 1/4885NQO2 406/4885 |
| US-20070123529-A1 | Substituted biphenyl compounds | MTNR1A, MTNR1B, CNR1 | MTNR1B 2/4885MTNR1A 1/4885NQO2 522/4885 |
| US-20040002491-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | CYP4B1, CYP3A5, MC2R | MTNR1B 325/4885MTNR1A 388/4885NQO2 492/4885 |
| US-20040002490-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | CYP3A5, CYP4B1, MC2R | MTNR1B 340/4885MTNR1A 409/4885NQO2 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.