Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379847 | 0.92 | MMP2 (0.41) | MMP8MMP2MMP1MMP14ANPEP | |
| SCHEMBL5450417 | 0.90 | MMP2 (0.39) | MMP8MMP2MMP1ANPEPLTA4H | |
| SCHEMBL5345342 | 0.89 | MMP2 (0.44) | MMP8MMP2MMP1MMP14ANPEP | |
| SCHEMBL5319634 | 0.88 | MMP2 (0.43) | MMP8MMP2MMP1ANPEPLTA4H | |
| SCHEMBL5378455 | 0.88 | MMP2 (0.42) | MMP8MMP2MMP1SLC6A2SLC6A4 | |
| SCHEMBL5338202 | 0.87 | CTSS (0.36) | MMP2MMP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5323550 | 0.86 | MMP2 (0.44) | MMP8MMP2MMP1ANPEPLTA4H | |
| SCHEMBL5462225 | 0.86 | MMP2 (0.39) | MMP8MMP2MMP1MMP14ANPEP | |
| SCHEMBL5318825 | 0.86 | MMP2 (0.42) | MMP8MMP2MMP1ANPEPLTA4H | |
| SCHEMBL5373840 | 0.85 | MMP2 (0.37) | MMP8MMP2MMP1MMP14ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | claimed |